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which functions primarily in peroxisomal beta-oxidation of straight-chain saturated acyl-CoA fatty acids 27,28 and can be induced by ligands of the nuclear receptor peroxisome proliferator ...
Panel C shows the relation between microsomal ω-oxidation, peroxisomal β-oxidation, and mitochondrial β-oxidation, as well as the regulatory role of peroxisome-proliferator–activated receptor ...
Peroxisome proliferator-activated receptor ... Bezafibrate for an inborn mitochondrial beta-oxidation defect. N Engl J Med. 2009;360(8):838-840. doi: 10.1056/NEJMc0806334 40.
A recent metabolomics study found that impaired peroxisomal oxidation of polyunsaturated fatty acids is associated with the progression of nonalcoholic fatty liver (NAFL) to nonalcoholic ...
While the PAL pathway also involves β-oxidation, its exact mechanism remains ... we discovered that HSR201 predominantly localizes in the peroxisome, a finding that was quite unexpected ...
In his latest study, Rachubinski found another clue in the search to understand the peroxisome and the disorders caused by its malfunction. He and his team discovered that a protein family thought ...
It’s called the peroxisome, and it’s the Swiss army knife of membrane-bound organelles. “I like to think of it as the room in the house that could be an office, a nursery or a gym, whatever the cell ...
These organelles fulfill critical protective functions in the cell and are vital for health, according to the scientists, who add that the loss of peroxisome function and dynamics leads to severe ...
A recent metobolomics study by researchers from Virginia Commonwealth University Medical Center in Richmond found that impaired peroxisomal oxidation of polyunsaturated fatty acids (PUFA ...