Key Laboratory of Marine Drugs of Ministry of Education, Shandong Key Laboratory of Glycoscience and Glycotherapeutics, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, ...

Beta-lactam antibiotics are the most widely used group of antibiotics, they target the penicillin-binding proteins (PBPs), eventually disrupting the peptidoglycan synthesis. To combat these ...

After treatment with lactoferrin, S. aureus cells were less covered (P 0.05) with wheatgerm agglutinin labelled with gold, thus suggesting that lactoferrin affected the synthesis of peptidoglycan ...

The pathway starts in the cytosol with the synthesis of two UDP-activated precursors UDP-GlcNAc and UDP-MurNAc-pentapeptide (see figure). This is followed by the assembly of the complete peptidoglycan ...