Ligand binding shifted the loop connecting the β3 and β4 strands by approximately 5–7 Å towards the peptide hormone. Phe72 in that loop shifted in the ligand bound structure by 7.2 Å and ...

The metals had subtle effects on the structure of C-peptide, notably on its ability to curl into a helix in some conditions. Copper and chromium prevented cells from taking up the hormone, but other ...

Tufts University scientists are aiming to revolutionize the future of weight loss drugs by engineering a new compound that ...

The metals had subtle effects on the structure of C-peptide, notably on its ability to curl into a helix in some conditions. Copper and chromium prevented cells from taking up the hormone ...

Semaglutide, a synthetic analog of glucagon-like peptide-1 (GLP-1), has garnered attention for its intriguing properties and potential implications in various r ...

Structure Solves Mystery To determine ... The team first coaxed the FGF23 hormone, along with its receptor protein (FGFR) and αKlotho, to settle out of a solution and form stacks of repeating ...