Antigen-presenting cells work to present peptides derived from exogenous and endogenous antigens to circulating T cells, sparking off an immune response. Dendritic cells are unique amongst antigen ...

More studies will be needed to further dissect this mechanism and determine whether specific molecular features of peptide antigens promote this process. Furthermore, several versions of STING are ...

During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and ...

New research shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own. The study provides a better understanding of immune ...

If the peptides are foreign antigens, the T cells expand in numbers and transform into an activated state, specialized to eradicate the pathogen. If the dendritic cell is carrying a "self-peptide ...

Peptide-based vaccines deliver tumor-specific antigens to dendritic cells (DCs), triggering tumor-targeted T-cell responses. A peptide-peptide conjugate technology previously developed by researchers ...

The firms hope to show that Verdi's off-the-shelf peptide cancer vaccine can shrink tumors and improve quality of life in patients with bone metastases.

Topas Therapeutics today announced the publication of data highlighting the ability of its proprietary antigen-coupled nanoparticles’ to achieve tolerance induction in relevant autoimmune disease ...

The initial antigens were identified from bacteria in ... Zhao: We did identify a dominant B-cell peptide epitope in CD patients, located in the highly conserved hinge-region between the D0 ...

the direct pathway (intact donor MHC molecules displayed on donor antigen-presenting cells [APCs]) and the indirect pathway (donor peptides bound to self-MHC molecules on recipient APCs).