“In particular, whole-cell patch clamp revolutionized classical electrophysiology,” remarked Neher. Subsequently, the groups developed two other configurations that could be performed once they ...

The technique, called whole-cell patch-clamp electrophysiology ... "The intrinsic excitability, a proxy for how readily a neuron can talk to other neurons, of pyramidal neurons was changed ...

Here, using patch-clamp electrophysiology techniques, I examined the structure-function of pentameric ligand-gated ion channels. My time in Dundee included a short post-doctoral position (JBC, 2008 ...