Specific DNA 18-mer sequences used for primer extensions are 5′−TGCATTTGTCACTGGAAC-3′ for the guide strand and 5′-GGTGAGGTTCCAGTGAC-3′ for the passenger strand of 22siRNA. For ...

The other strand, known as the passenger strand ... the addition of single-carbon methyl groups to the transcribed DNA, leading to changes in gene organization that prevent further rounds of ...

"If this affects DNA strand separation, all protein interactions with DNA are also going to be affected," Marko said. "For example, the tendency for proteins to stick to specific sites on DNA and ...

Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to ...

On their own, however, polymerases aren't good at staying on the DNA strand. They require CTF18-RFC in humans and Ctf18-RFC in yeast to thread a ring-shaped clamp onto the DNA leading strand ...

The new study is based on the understanding that DNA is made up of two strands of molecular letters, or bases. Each strand is composed of four types of letters: adenine (A), thymine (T), guanine ...

HBV is a partially double-stranded DNA virus. The life cycle and therapeutic targets are shown in Figure 1 and Figure 2. The spherical 42-nm virion comprises an envelope that is outside a 30-nm ...