Cells are constantly subjected to DNA damage from a range of internal and environmental sources. It is estimated that cells ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

The other strand, known as the passenger strand ... the addition of single-carbon methyl groups to the transcribed DNA, leading to changes in gene organization that prevent further rounds of ...

Macquarie University researchers have discovered a naturally occurring protein found in human cells plays a powerful role in ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together ... More —like superglue— and creates a safe zone for other proteins to come repair the damage.

Experiments with tools designed to detect DNA damage reveal unique and conserved features of telomeres in cancer cells.

On their own, however, polymerases aren't good at staying on the DNA strand. They require CTF18-RFC in humans and Ctf18-RFC in yeast to thread a ring-shaped clamp onto the DNA leading strand ...

Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to ...

Researchers at Northwestern University found that DNA strand separation may require more force than previously thought when modeled in a more true-to-life environment. In most labs, scientists ...

"If this affects DNA strand separation, all protein interactions with DNA are also going to be affected," Marko said. "For example, the tendency for proteins to stick to specific sites on DNA and ...

First, they fabricated a universal single-strand DNA, as well as library of hundreds of short, single DNA strands called bricks. Each brick is composed of 24 nucleotides, including cytosine sites ...