Jennifer Klomp and colleagues 7 used advanced mass-spectrometry techniques to map the ERK-dependent phosphoprotein ... do not sufficiently displace PI3K from active KRAS. In addition, active ...
The laboratory is studying small molecules that selectively inhibit the components of RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. These compounds are being used as reagents to define the role of these ...
A groundbreaking review highlights significant advancements in the understanding and treatment of cerebral vascular ...
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