This assay combines PCR and DHPLC and can be used to conduct efficient genotyping of the human population, which in turn will help in the diagnosis and treatment of Alzheimer's disease.

PCR for the fragments was conducted according ... Minisequencing primers design and primer-extension reactions for DHPLC The sequence of the minisequencing extension primer used in this study ...

Duplexes for DHPLC analysis were created by mixing PCR products from a healthy subject with the corresponding amplicon of the PXE patients. The wild-type sequence of the normal control was ...

Alternatively, DHPLC approach reveals the presence of genetic variation by the differential retention of the homo- and heteroduplex DNA molecules on ion-pair reversed-phase high-pressure liquid ...

Researchers have developed a light-induced DNA detection method that enables rapid, PCR-free genetic analysis. Their technique offers ultra-sensitive mutation detection in just five minutes ...