在生病用药期间，有一个关于饮食的提醒需要引起大家的重视——尽量避免食用西柚。这并不是无的放矢，而是有科学依据的。西柚，这种看似清新可口的水果，实际上具有影响药物代谢的能力，甚至可能威胁到我们的健康。

However, for decades, those on certain medications have been advised to avoid this citrus fruit because it could interfere ...

One of the isoforms of P450, CYP3A4, is found in the gut wall, and it metabolizes drugs such as the immunosuppressant cyclo- sporin, the calcium channel blockers felodipine, nifedipine ...

CONCLUSIONS: Cytochrome P450 3A4 is a primary enzyme responsible for the metabolic clearance of quetiapine. Quetiapine pharmacokinetics were affected by concomitant administration of ketoconazole ...

The drug is cleared by cytochrome P450 (CYP)3A4 metabolism. Peak plasma concentrations are achieved about 1.5 hours after oral administration. Its absorption is not affected by food. Eplerenone ...

Of particular importance are cytochrome P450 enzymes, heme-containing mono ... that are toxic or carcinogenic 2. The level of CYP3A4 expression may determine which patients best respond to certain ...

This could change the effects and side effects of these medications. Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with QUERCETIN Some medications are ...

Opioid analgesic risk evaluation and mitigation strategy (REMS); Cytochrome P450 3A4 interaction; For oral solution: Risk of medication errors. Assess the potential need for access to naloxone ...