By Dennis Thompson HealthDay ReporterFRIDAY, June 6, 2025 (HealthDay News) — There’s a better option than daily aspirin to ...

The NHS is recommending the use of aspirin to help prevent heart attacks and strokes for those vulnerable to them. For anyone that is considered high-risk of either, aspirin contributes to the ...

The adenosine diphosphate receptor P2Y12, found on the surface of platelets, plays an important role in this essential mechanism. It belongs to the family of so-called G-protein-coupled receptors ...

MUNICH, Germany—A new analysis from the large SCAAR registry in Sweden is once again challenging the role of pretreatment with oral P2Y12 receptor antagonists in PCI patients, this time zeroing in on ...

Idorsia's P2Y12 receptor antagonist selatogrel has significantly inhibited platelet aggregation in two phase 2 trials. The primary endpoint successes in patients with stable coronary artery ...

The drug is a highly selective and potent 2-phenylpyrimidine-4-carboxamide analog that can reversibly bind with P2Y12 receptor antagonists. Prior research in healthy adults showed a quick and robust ...

Clopidogrel inhibits platelet aggregation via specific inhibition of the adenosine-5-diphosphate (ADP) P2Y12 receptor. Currently marketed tests measure the ability of ADP to activate platelet ...

"The mechanism of action is expected to be specific to ticagrelor and not work with clopidogrel [Plavix] or prasugrel [Effient], which are irreversible P2Y12 receptor antagonists." As for safety ...