The ribosome is one of the primary antibiotic targets in the bacterial cell. Here, Daniel Wilson discusses how high-resolution crystal structures of antibiotic–ribosome complexes have provided ...

Contrastingly, yeast ribosomes are comprised of a 40S and 60S subunit, which assemble to form the 80S structure. Each subunit across species contains three sites that underpin the translation process.

PSR Role in T-Cell Recognition: The study reveals that P-stalk ribosome (PSR) knockdown dramatically reduces CD8+ T cell recognition of tumor antigens, underscoring the central role of PSRs in ...

Johns Hopkins researchers, reporting in the journal Nature January 7, have discovered a new "proofreading step" during which the suite of translational tools called the ribosome recognizes errors ...

Ribosomes synthesize all the proteins in cells. Studies mainly done on yeast have revealed much about how ribosomes are put together, but a team now reports that ribosome assembly in human cells ...

Key to the new molecule’s success is its improved ability to bind to bacterial ribosomes. Many antibiotics kill bacteria by disrupting ribosomal function. However, some superbugs have evolved ...

albicans ribosome, with the insert showing inhibitor CHX (purple structure) in the ribosome E-site. The original structure is in blue and the structure with the proline to glutamine mutation in beige.

Building a ribosome requires a complex pathway that involves a diverse array of molecules, including a family of proteins called AAA-proteins, for ATPases Associated with diverse cellular Activities.

DNA gets all the glory, but genetic material wouldn’t be anywhere without ribosomes — cellular protein factories that build everything from insulin to fingernails. The Royal Swedish Academy of ...

Study: P-stalk ribosomes act as master regulators of cytokine-mediated processes.Image Credit: ALIOUI MA / Shutterstock. In a recent study published in the journal Cell, researchers conducted ...