Background: tudies of the beneficial effects of antihypertensive therapy in diabetic nephropathy have largely focused on hypertensive patients with microalbuminuria or overt albuminuria. Objective ...

Indeed, in the AVOID study, aliskiren reduced the albumin to creatinine ratio in patients with T2DM and overt nephropathy who were already receiving the ARB losartan. 84 Unfortunately, a ...

3 If retinopathy is present, albuminuria can be attributed with confidence ... reducing the risk of the development or progression of overt nephropathy. The diabetes substudy of the Heart Outcomes ...

According to this model, when elevated urinary albumin excretion develops in persons with type 1 diabetes, it can remain static, advance toward overt proteinuria, or regress toward normal levels ...

Persistent albuminuria in the range of 30-299 mg/24 h (microalbuminuria) has been shown to be the earliest stage of diabetic nephropathy and is a significant risk marker for cardiovascular disease ...

However, controversy surrounds the use of estimated GFR (eGFR) and albuminuria to define chronic ... values of 33.9 (the threshold for defining overt albuminuria, often termed macro-albuminuria).

A Growing Double BurdenThe rising prevalence of prediabetes and chronic kidney disease (CKD) in India reflects an ...

The addition of high-dose eplerenone may reduce urinary albumin excretion with an acceptable safety profile to type 2 diabetes patients at high risk for cardiovascular disease.

Researchers in Italy developed and validated a new model that identified patients with cirrhosis at risk for developing overt hepatic encephalopathy, according to published findings.“In this ...

A meta-analysis of more than a million people in populations across Europe, the USA, Australia, and Asia has shown that both glomerular filtration rate (GFR) (the rate at which blood is filtered ...