The TS ribozyme (originally called “twister sister”) is a catalytic RNA. We present a crystal structure of the ribozyme in a pre-reactive conformation. Two co-axial helical stacks are ...

We present a crystal structure at 2.3-Å resolution of the recently described nucleolytic ribozyme twister. The RNA adopts a previously uncharacterized compact fold based on a double-pseudoknot ...

Important progress for RNA research: A team has discovered a new ribozyme that can label RNA molecules in living cells. RNA molecules are real all-rounders. They transfer the genetic information ...

Atomic-resolution Structure Of A Ribozyme Yields Insights Into RNA Catalysis And The Origins Of Life Date: July 22, 2006 Source: University of California - Santa Cruz Summary: Scientists have ...

Scientists at UCSC's RNA Center have now obtained a near-atomic resolution image of the three-dimensional shape of a very simple--and therefore potentially understandable--ribozyme in which the ...

The team analysed this ribozyme’s biochemical properties and secondary structure and concluded it belongs to a new class of ribozymes, expanding our picture of ribozyme diversity. This is the first ...

Important progress for RNA research: A team led by Würzburg chemistry professor Claudia Höbartner has discovered a new ribozyme that can label RNA molecules in living cells.

Scott’s structural observations of the hammerhead ribozyme, however, could not explain a growing number of biochemical experimental results. The hammerhead ribozyme has been the subject of intensive ...

Directed evolution yields an RNA polymerase ribozyme that can both replicate and transcribe RNA and thus support an RNA world. genprowebdirectory Facebook Linkedin RSS Twitter Youtube ...

A SAM analogue-utilizing ribozyme for site-specific RNA alkylation in living cells. Nat Chem. 2023. doi: 10.1038/s41557-023-01320-z. This article has been republished from the following materials.

The research team also identified the first example of a twister ribozyme in mammals, specifically in the genome of the bottlenose dolphin. A paper describing the study appeared online today, Nov ...

Being the first U.S. FDA-approved ribozyme-based RNA reprogramming approach to be evaluated in patients, RZ-001, a gene therapy approach utilizing the company's proprietary trans-splicing ribozyme ...