Nucleic acid therapeutics are based on nucleic acids or closely related chemical compounds. They include antisense oligonucleotides, aptamers and small interfering RNAs, and are typically ...

Nucleic acid therapeutics use engineered sequences ... that skip key protein instructions or include unwanted sequence elements. A well-designed ASO can overcome this. “You’re using them ...

Unlike antibodies, aptamers' unique structures include hairpin regions (red), which provide stability. The image also highlights chemical modifications (yellow) that increase durability, and biotin ...

DNA is fundamental to the biology of all life on Earth, but how many of us actually know what it is or what it's made of?

The Nucleic Acids Institute is dedicated to understanding the chemical and biological basis for nucleic acid function, and to developing new and powerful nucleic acids based therapeutic and ...

The interest groups are member driven groups that exist to benefit RSC members, and the wider chemical science community, in line with the RSC's strategy and charter. The group was formed in 2003, ...

Professor Kojima-Yuasa's team used compounds of nucleic acids derived from salmon milt DNA and torula yeast RNA and showed that chemical compounds like guanosine could prevent the proliferation of ...

Scientists have uncovered a surprising role for calcium in shaping the building blocks of life. Their study reveals that calcium ions help determine the molecular 'handedness' (chirality) of tartaric ...