A cell signaling mechanism of fundamental importance to animal development is the Notch pathway (Figure 1). It may be safely said that Notch signaling is required, in some reasonably direct fashion, ...

本研究旨在探讨Slit2对体外血管内皮细胞增殖和迁移的影响，并揭示可能的潜在信号通路。从Sprague Dawley大鼠身上分离主动脉内皮细胞并进行培养。随后进行细胞增殖试验、细胞迁移试验、免疫细胞化学和小干扰RNA转染。结果表明，外源性Slit2可显著抑制TNF - α诱导的内皮细胞增殖和体外迁移。（本段内容为AI翻译，原始内容请见官网） ...

Research carried out in Montreal is providing a better understanding of how an essential component of the immune system works ...

Northwestern Medicine investigators have identified novel mechanisms regulating the development of the spinal column during ...

Researchers have identified novel mechanisms regulating the development of the spinal column, which could inform new ...

The scientists found how this summons non-native monocytes to the liver, and how Notch signaling transforms them into ...

Specifically, we would like to understand how these glycosyltransferases regulate the activity of the Notch signaling pathway in a dosage-sensitive and tissue-specific manner. We have reported a mouse ...