For instance, Notch signaling specifies the wing margin, a line of cells that organizes the patterning and outgrowth ... BEN-solo factors partition active chromatin to ensure proper gene activation in ...

By using the Drosophila pupal wing, we are interested in elucidating how tissue morphogenesis and dynamic cellular communications are regulated at the subcellular level. Osamu is a Principal ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

Genetic screens in Drosophila melanogaster pioneered the discovery of core PCP factors, which regulate the orientation of hairs on wings and facets in eyes. Recent genetic evidence shows that the ...