S-Nitrosylation involves the transfer of a nitroso group to cysteine residues, resulting in the formation of S-nitrosothiols (SNO). This reversible post-translational modification dynamically ...

The process of NO-protein modifications—known as S-nitrosylation—was first described by Lipton and collaborators some 20 years ago. S-nitrosylation has important regulatory functions under ...

CaMKII is a protein that helps control brain activity, especially in areas that manage memory and learning. As we age, the ...

Sun Baolin from the University of Science and Technology of China (USTC) revealed the mechanism of transcriptional regulation via S-nitrosylation for vancomycin resistance in Staphylococcus aureus.

A new study from researchers at Moffitt Cancer Center shows that blocking a chemical process called nitrosylation could make one of the most aggressive forms of melanoma more treatable. Their ...

A new study from researchers at Moffitt Cancer Center shows that blocking a chemical process called nitrosylation could make one of the most aggressive forms of melanoma more treatable. Their research ...

Central to the dysfunction is the aberrant modification of mitochondrial enzymes by S-nitrosylation, a chemical reaction where nitrogen and oxygen atoms bind to sulfur atoms on proteins.

Using cultured brain cells from mice and humans, the researchers first confirmed that excess NO leads to S-nitrosylation of CRTC1. They then discovered that this chemical modification prevented ...

Using cultured brain cells from mice and humans, the researchers first confirmed that excess NO leads to S-nitrosylation of CRTC1. They then discovered that this chemical modification prevented ...