中性粒细胞和巨噬细胞是抵御病原体微生物感染的重要免疫细胞。在病原体入侵时,中性粒细胞率先被招募到感染部位,通过吞噬、产生活性氧(ROS)等方式发挥抗菌作用,同时其释放的 NETs 也备受关注。NETs 由双链 DNA、组蛋白和非组蛋白蛋白质组成,在调节免疫反应中发挥重要作用。巨噬细胞则可分化为 M1 和 M2 两种类型,M1 型巨噬细胞分泌促炎细胞因子,增强免疫反应;M2 ...
Neutrophils are a type of white blood cell that play a crucial role in the body's innate immune response, acting as the first line of defense against infections and inflammation. One of the key ...
neutrophil extracellular traps)的释放,然而,NET释放对于Mtb致病机制的分子调节和影响背后的分子机制,目前研究人员并不清楚。 近日,一篇发表在国际 ...
They are well-equipped to combat invaders such as bacteria or fungi by engulfing the invaders, releasing antimicrobial substances, or forming web-like traps known as "neutrophil extracellular traps." ...
Their arsenal of defense mechanisms includes engulfing intruders like bacteria or fungi, secreting antimicrobial agents, and ...
A pioneering study has uncovered the complex and dual roles of neutrophils in cancer development, demonstrating their remarkable ability to both stimulate and suppress tumor growth. This research ...
Rigel Pharmaceuticals (RIGL) announced the first patient has been enrolled in a Phase 1 study evaluating the safety and tolerability of ...