Yet this variability does not prevent the brain from functioning reliably. This paradox, known as "neuronal degeneration," has intrigued scientists for decades. This concept is different from ...

A new drug-free, minimally invasive intervention targets the root cause of progressive loss of neural function in spinal ...

4 In 1967, the term 'corticodentatonigral degeneration with neuronal achromasia' was introduced to describe three individuals who presented with progressive awkwardness and slowness of voluntary ...

This technology selectively marks neuronal membranes, allowing for the visualization of neuronal structures and real-time monitoring of neuronal changes. Neurons are nerve cells that transmit ...

Neural transplants used to treat Huntington disease (HD) show disease-like degeneration in the long term, despite seeming to be successful and healthy initially. Francesca Cicchetti, Thomas ...

This genetic treatment reduced bowel symptoms and extended the lifespan of the mice by preventing enteric neuron degeneration. The findings, published Jan. 15 in Science Translational Medicine ...

Therefore, the biological burden or propensity for neural degenerative and regenerative processing is enhanced in the brain. The degenerative events include neuronal death and synaptic loss ...

Researchers from the University College Cork have described the neuroprotective effect of TMP-269, a class-IIa-specific histone deacetylase (HDAC) inhibitor in preclinical models of PD. Pan-inhibitors ...

Amyloid plaques, accumulations of toxic proteins in the brain, play a central role in neuronal degeneration. Despite advances, no treatment effectively targets these plaques or the associated brain ...