Neuroblastomas are embryonal tumours of the sympatho-adrenal lineage with a clinical course ranging from spontaneous regression to fatal progression. The Phox2B homeobox transcription factor ...

A predisposition locus has been mapped to the short arm of chromosome 16. Neuroblastomas can be classified into subtypes that are predictive of clinical behaviour based on the patterns of genetic ...

Although many lower-stage neuroblastomas are encapsulated and can be surgically excised with little chance of complications, higher-stage tumors often infiltrate local organ structures ...

As shown in Table 1 and Appendix Figure A1 and summarized below, UH neuroblastomas are classified into four subgroups. Taken together, targeting TERT, MYCN/MYC, and ALT via ATRX would contain the stem ...

Prognostic Factors for Leukemic Induction Failure in Children With Acute Lymphoblastic Leukemia and Outcome After Salvage Therapy: The FRALLE 93 Study For infants with localized neuroblastoma without ...

For patients with high-risk neuroblastomas, the five-year survival rate is 40 to 50 percent even with the most rigorous treatments available today. Neuroblastoma is one of the deadliest childhood ...

Dr Yihua Wang from the University of Southampton, a senior author on the paper said: "This research represents a pivotal advancement in our understanding of MYCN non-amplified neuroblastomas.

Anna Children's Cancer Research Institute have discovered. Together with colleagues from the Medical University of Vienna and the University of Vienna (Faculty of Chemistry), they studied tumors of ...

Neuroblastoma is a devastating solid tumor of childhood and emerges in the sympathetic nervous system while many kids who develop it are still toddlers. Now, medical scientists in China who are ...

The researchers from the Wellcome Sanger Institute, Great Ormond Street Hospital (GOSH) and the Princess Máxima Center for Pediatric Oncology, discovered that all neuroblastomas arise from a single ...

Because of their neuronal origin, neuroblastomas synthesize and release neuropeptide Y (NPY), a small protein normally secreted from mature nerves. In previous research, Kitlinska and her ...

The mice had spontaneous neuroblastomas, which were very similar to the human versions. Researcher Michelle Haber of the Children's Cancer Institute Australia and president of the ANR association ...