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The mouse mutants do not support a simple morphogen model — such as the Shh model that has been proposed for the ventral neural tube — for dorsal neural tube patterning. However, recent ...
A developing mouse neural tube. Hedgehog signalling is required to produce different types of neuronal progenitor cells, indicated by the different colours. THC inhibits Hedgehog signalling in ...
"Neural tube defects can be caused by variants in over 300 genes in the mouse, so we anticipate that many genes also are likely to be involved in the human condition." ...
A research team led by Monita Wilson, Ph.D., found neural tube defects in some mouse embryos from female mice genetically modified to have low levels of ITPK1, an enzyme involved in the metabolism ...
Other mouse embryos in the study were found to have ... to have children but who have had previous pregnancies with neural tube defects in which some of the participants take folic acid and ...
A research team led by Monita Wilson, Ph.D., found neural tube defects in some mouse embryos from female mice genetically modified to have low levels of ITPK1, an enzyme involved in the metabolism ...
The National Institute of Health (NIH) announced on Aug. 25, 2022, that scientists funded in part by the NIH have successfully generated a mouse embryo model, or embryoid, that develops beyond the ...
This applies pressure to the neural plate from the side and causes it to passively form into a tube. The researchers arrived at these findings with the help of computational modelling. Using existing ...
Chinese scientists have outlined the largest depiction so far of mouse cells in the hippocampus ... a wide range of tools to analyze the entire neural roadmap. They reconstructed a map of 10,100 ...
Babies who were exposed to certain organic pollutants in the womb are at a highly increased risk of neural tube defects leading to conditions such as spina bifida, according to researchers in China.
A primary ongoing aim of the surveillance is to evaluate the prevalence of neural-tube defects associated with exposure to antiretroviral drugs from the time of conception (the risk period for ...
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