Necroptosis is a form of programmed necrosis. Necroptotic stimuli promote the interaction of the RIP1 and RIP3 kinases under conditions in which caspase-8 is not active. This RIP1/RIP3 complex ...

Apoptosis is triggered many different ways, but they all ultimately activate enzymes known as caspases that disrupt a cell’s DNA, organelles, and cytoskeleton ... even proliferating within their ...

A study has uncovered that iron orchestrates the activation of two damaging cell death pathways—ferroptosis and ...