Necroptosis is a form of programmed necrosis. Necroptotic stimuli promote the interaction of the RIP1 and RIP3 kinases under conditions in which caspase-8 is not active. This RIP1/RIP3 complex ...

A cell in yellow is shown dying by necroptosis, a process requiring the protein MLKL Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert!