本文聚焦坏死性凋亡（Necroptosis）、自噬（Autophagy）和 Parthanatos 这三种程序性细胞死亡机制，它们与脑部健康和疾病密切相关。文章总结了其在脑部疾病发病机制中的研究数据，探讨了相关实验模型及治疗方法，有助于推动中枢神经系统疾病防治研究。 坏死性 ...

inhibition of necroptosis may be seen as providing a good therapeutic option in the acute phase of the disease. Inflammatory myopathies are systemic diseases which can affect the skin, lung ...

inhibition of necroptosis may be seen as providing a good therapeutic option in the acute phase of the disease. Inflammatory myopathies are systemic diseases which can affect the skin, lung ...

Now, necrosis is known to have programmed aspects, with “necroptosis” describing regulated necrotic cell death. Apoptosis and necrosis are characterized by different mechanisms leading to cell ...

BUFFALO, NY- April 24, 2023 – A new editorial paper was published in Oncotarget's Volume 14 on April 10, 2023, entitled, “Tumor necroptosis promotes metastasis through modulating the interplay ...

“Arsenite in combination with interferon as a cancer treatment promotes anti-cancer immunity, and necroptosis is known to be very good at promoting such immunity. The findings in this paper may ...

Tumor cell deaths can benefit tumors. A paradox? Not at all. If, for example, a dying tumor cell undergoes necroptosis, it can release inflammatory factors that can enhance or diminish antitumor ...

Nerve cells die in the context of Alzheimer's disease as a consequence of a well-defined sequence of biochemical reactions, called 'necroptosis.'" Dr. Sriram Balusu, Postdoctoral Researcher ...

To address this issue, Prof. Nakano's group previously developed a biosensor for necroptosis called SMART (Sensor for MLKL activation by RIPK3 based on FRET). This biosensor is designed based on ...