The CPA produced by naloxone was compared with that produced by the neutral antagonists 6-alpha- and 6-beta-naloxol in mice with and without prior morphine exposure. While all three drugs produced ...

Co presented positive results this week from Phase 1 and preclinical studies of NKTR-118 (oral PEG-naloxol) at the American Academy of Pain Management meeting. Data from a single-dose, proof-of ...

The drug combines Nektar’s small molecule polymer conjugate technology platform with naloxol, a derivative of the opioid-antagonist, naloxone. Nektar claims its advanced polymer conjugate ...