and the adoption of state-of-the-art automated structure determination protocols by the wider bio-NMR community. We look forward to a fascinating experiment.

Structure determination by NMR typically requires a protein concentration of 0.5 mM or greater, stable for several days at the desired temperature, usually 20-40 o C. Proteins and peptides should be ...

NMR can identify different nuclei in a molecule and analyze large proteins and other large molecules using ... double and triple resonance experiments developed to perform NMR structure determination ...

NMR spectroscopy has gained acceptance in the last few decades as a powerful technology for protein structure determination, but it is limited to small (<40 kDa), stable, soluble proteins that do ...

The acquisition of standard NMR spectra takes from a few minutes (1D spectra) to 3/4 days (3D or 4D spectra) for each experiment. A full set of experiments for protein structure determination usually ...

Nearly every element has at least one isotope that is NMR active. Since then, NMR spectroscopy has become an indespensible tool for the determination of molecular structure, the study of molecular ...

The new 1.2 GHz NMR complements the existing 800 MHz NMR in Basel and other high-field NMRs for protein structure determination, measurement of protein dynamics, ligand binding studies ...

This work includes using in cell NMR, a technique to study the structure and dynamics of proteins within living cells. I currently study intrinsically disordered proteins using solution NMR. Proteins ...

These efforts have led to the determination of the structure of a phosphorylated bacterial protein and cytochrome b5. The NMR research was integrated, in part, into a course he teaches: "Organic ...

Visualization of the protein clumps associated with Huntington ... Miettinen: Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease.