As such, many of the well-established metabolic factors that drive NAFLD progression would be ignored. The same patient would, however, meet the criteria for MAFLD, and the fact that they have HBV ...

Non-alcoholic fatty liver disease (NAFLD) represents the most common liver disease worldwide affecting approximatively 20–30% of the general population. The histopathological and clinical ...

Nonalcoholic fatty liver disease (NAFLD) and its progressive form, nonalcoholic steatohepatitis (NASH) are the most common causes of chronic liver disease in industrialized countries. NAFLD has ...

noninvasive biomarkers for the evaluation of disease severity and progression, lifestyle-related patients' recommendations, risk prediction of disease by genetic testing, management of NAFLD ...

Philadelphia, March 6, 2025 – Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) into more ...

The gene Asah1 plays a crucial role in preventing the progression of nonalcoholic fatty liver diseases (NAFLD) to more severe forms by regulating lipid homeostasis and cellular maintenance.

NAFLD includes a spectrum of liver disorders ... and lack of physical activity contribute significantly to disease ...

#liverdisease’ Impaired lysosomal function (breaking down waste) leads to accumulation of excess lipids in liver cells, worsening NAFLD and contributing to its progression. By analyzing a ...

These findings demonstrate that Asah1 plays a crucial protective role in preventing the progression from simple NAFLD to more severe forms of liver disease (fibrotic NASH) by regulating hepatic ...