Here, we show that a fraction of blood monocyte-derived myeloid dendritic cells (MDCs) express B7-H1, a member of the B7 family, on the cell surface. B7-H1 could be further upregulated by tumor ...

Tumours directly affect mature myeloid cells by converting some of them into immunosuppressive populations that facilitate tumour growth. In cancer, normal myeloid cell differentiation is also ...

Patients with blood cancers like polycythemia vera, a kind of myeloproliferative neoplasm, may benefit in learning more about ...

Dendritic cells (DC) are a type of antigen-presenting ... and response to inflammation or infection. The myeloid DCs differentiate from monocytes and macrophages in the presence of cytokines ...

Scientists have discover that 'elite controllers' have myeloid dendritic cells that display characteristics of trained innate immune cells. Immunity often calls to mind the adaptive immune ...

In primates, the dendritic cells are usually divided into two main groups: the myeloid dendritic cells (mDCs) and the plasmacytoid dendritic cells (pDCs). Also called conventional dendritic cells ...

In June 15 Journal of Immunology Holger Hackstein and colleagues from the Thomas E. Starzl Transplantation Institute at the University of Pittsburgh show that aspirin targets the dendritic cells ...

Myeloid lineage cells, including macrophages, dendritic cells, osteoclasts and precursor cells, all produce VEGF-C in response to inflammatory cytokines, which is mediated by the canonical NF-κB ...

In this article, we consider what dendritic cells (DCs) are, how they are generated, their function in the body and some medical conditions related to them. DCs are named for their distinctive ...

Multipotent progenitor cells are those with the potential to differentiate into a subset of cell types. These cells then differentiate into either the common myeloid progenitor (CMP) or common ...