LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

Your body is a collection of cells carrying thousands of genetic mistakes accrued over a lifetime—many harmless, some bad and at least a few that may be good for you ...

This means that the damage has multiple chances to generate harmful mutations, which can lead to cancer. While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms ...

A new study has uncovered a direct link between somatic mutations and epigenetic modifications, challenging established views ...

"Missense" mutations — changes in a DNA sequence that swap one amino acid ... it's not entirely clear how these mutations affect the structure and function of proteins and thus cause disease.

A new mega-database of half a million mutations may flag new ways of treating genetic disease, scientists say.

Researchers uncovered unexpected patterns of mutation inheritance in the trees, revealing that some DNA damage persists unrepaired. In the case of blood stem cells, this can be for two to three years.