Sequestration does not affect the monomer steady-state value Profilin is a major regulator of actin assembly that binds ATP–G-actin with high affinity. Profilin–actin exclusively feeds barbed ...

The dynamic interchange between monomeric G-actin and polymeric F-actin filaments is fundamental to cell motility and cytokinesis. Actin filament dynamics is regulated by numerous actin-binding ...

The assembly of this cytoskeleton is controlled at many levels including globular actin monomers (G-protein) undergoing reversible polymerization into actin polymers and the superorganization of ...

Among the novel advances are characterization of the normal stepping across 13 actin monomers and the not-infrequent "misstepping" across 11 monomers that causes the myoV to rotate along the ...

Actin monomers act as building blocks by polymerising into rod-like filaments that push the leading edge of the cell forward. The polymerisation of the actin filaments must be balanced by ...

"In that experiment, we took two myosin VI monomers and 'zippered' their tops together to form a dimer – which then walked along the actin," Selvin said. "Some researchers thought that by ...