WE wish to suggest a structure ... of deoxyribose nucleic acid. This structure has two helical chains each coiled round the same axis (see diagram). We have made the usual chemical assumptions ...

Nucleic acid therapeutics are based on nucleic acids or closely related chemical compounds. They include antisense oligonucleotides, aptamers and small interfering RNAs, and are typically ...

The structure and chemistry of nucleic acids is fundamental to their function, from the DNA double helix discovered by Watson and Crick to the intricate secondary and tertiary structures adopted by ...

In DNA, two complementary strands of nucleotides pair up through hydrogen bonds between the bases (A with T and G with C) to form the iconic double helix structure ... The resulting RNA molecule, ...

incorporated in 1917. Wolfgang Pauli, born 1900, discovered exclusion principle; Noble Prize in Physics (1945). James D. Watson and Frances H. C. Crick published "Molecular Structure of Nucleic Acids: ...

The findings are detailed in the journal Nature Chemical Biology. Two of the most common building blocks in biology are nucleic ... acid in the peptide to convert the peptide into a ring structure ...

But James Watson and Francis Crick's claim was a valid one, for they had in fact discovered the structure of DNA, the chemical that ... that DNA, a nucleic acid, carries genetic information.

The findings suggest that some DNA regions, due to their open and active nature ... published in Nucleic Acids Research, ...