This question is difficult to answer at present because of a dearth of knowledge of chromosome structure beyond the nucleosome. Chemical cross-linking and X-ray studies performed with precisely ...

In fact, mutations in condensin structure can result in severe chromosome segregation defects ... to understand how additional factors, such as molecular regulators, affect this compaction process.

Daban, in the Department of Biochemistry and Molecular ... Micrometer‐Sized Chromosomes from the Perspective of the ...

In fact, mutations in condensin structure can result in severe chromosome segregation defects ... to understand how additional factors, such as molecular regulators, affect this compaction process.

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they ...

The nucleus of one of your skin cells contains about two metres of DNA, so a chromosome is a very large molecule compacted into a very small space. Watch the video below to see how DNA can be ...

A particular focus of the lab is to elucidate the molecular consequences of replication stress ... disrupts nucleosomes ahead of the fork raising the question how chromatin structure is maintained ...

How do cells manage to precisely duplicate their genetic material, especially in conditions of DNA damage? The ...