Small molecules can act at allosteric sites to directly activate the receptor (allosteric agonists) or to potentiate (positive allosteric modulators) or inhibit (negative allosteric modulators ...

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

High-speed optical modulator adoption is expected to increase from USD 43.2 billion in 2025. By 2035, it is projected to have ...

The full invitation to the AGM 2025 may be found in the General Meetings section of the Company's website here.

Discover the latest in cystic fibrosis treatment, from CFTR modulators to ENaC blockers and emerging inhalable gene therapies ...

Inmed Pharmaceuticals Inc. has divulged cannabinoid CB1 and/or CB2 receptor modulators reported to be useful for the treatment of neurodegeneration and age-related macular degeneration.

High-performance active terahertz (THz) modulators are of great importance for next generation communication technology. However, they currently suffer from the tradeoff between modulation depth ...

Raythera Inc. has identified TNF-α modulators reported to be useful for the treatment of inflammatory disorders, autoimmune disease, neurological disorders, pain, cardiovascular disorders, cancer, ...

This work, which spanned enzymatic, computational, and crystallographic studies, has uncovered mechanistic details that could inform the rational design of splicing modulators through structure ...

In the realm of test equipment, there are a number of items that you don’t know you need until you need one. That’s probably the case with the HP11720A pulse modulator. [Tom] acquired two of ...

Texas Instruments has launched the industry’s first functionally isolated modulators, enabling precise motor control in compact robotics with improved sensing accuracy and reduced board space.

Your doctor may prescribe serotonin-dopamine activity modulators, or SDAMs. These drugs – also known as second-generation antipsychotics, or atypical antipsychotics – are taken as a tablet or ...