Another important checkpoint takes place later in the cell cycle, just before a cell moves from G 2 to mitosis. Here, a number of proteins scrutinize the cell's DNA, making sure it is structurally ...

The goal of the mitotic cell cycle is to replicate the genome and pass identical copies to two daughter cells, so as to maintain genomic ploidy (number of chromosomes) from one generation to the next.

In mitosis, two cells called daughter cells are produced, each identical to the parent cell. When looking at cells with a microscope, the length of different stages of the cell cycle can be ...

Image Credit: DAntes Design/Shutterstock.com Understand The Full Cell Cycle Mitosis ... are microtubules, the mitotic spindle ...

Thus, it is well positioned to now turn its attention to understanding how quiescent non-cycling cells maintain themselves in a state in which it might be years before they re-enter the mitotic cell ...

A mechanosensitive nuclear checkpoint triggers cell cycle arrest after chromosome mis-segregation. Chromosome segregation errors during mitosis, induced for example by centromere dysfunction (the red ...

Damage-Induced Checkpoint Activation Regulation of the mammalian cell cycle is accomplished by multiple ... progression from G1 to cell division in mitosis. DNA damage-inducing agents such as ...

More about cancer biomarker for predicting response to drugs targeting mitotic checkpoint kinases and cell division Genomic instability – an increased tendency for DNA mutations and both structural ...

One poster demonstrating cell-free DNA molecular response as a potential surrogate endpoint to measure clinical efficacy of azenosertib in patients with high-grade serous ovarian cancer (HGSOC) Three ...