The OXPHOS system is under dual genetic control, which involves an interplay between the mitochondrial and the ... intergenomic communication, OXPHOS-complex assembly, import and energy homeostasis.

Isolated complex I deficiency was detected in muscle tissue and cultured fibroblasts. The boys died at 14 and 17 months from aspiration pneumonia 10. Neither cranial MRIs nor post-mortem reports ...

"By visualizing where these mutations occur and how they affect the structure and function of the RNase Z complex, we can understand the molecular basis of certain mitochondrial diseases ...

Methylation of mRNA leads to a change to its chemical structure so that ... that are synthesized by the mitochondria themselves. One of these is ND5, a subunit of complex I of the respiratory ...