Another intriguing issue that will need to be further addressed is the question of why functional mitochondria are lost in the neuronal terminals more than in the cell body. The authors propose ...

Mitochondria are the main suppliers of energy to neurons, but they look and behave differently depending on where they are situated in the brain cell. Mitochondria located in the axon, a neuron’s ...

Mitochondria are central to energy production in cells, and their dysfunction is increasingly implicated in the aging process and the pathogenesis of ...

The human brain is a complex powerhouse, responsible for orchestrating thoughts, emotions, and memories. Its nerve cells ...

An enzyme that helps clear damaged mitochondria can act as a molecular switch and potentially prevent neurons from dying.

Mitochondria organelles came from primordial bacterial endosymbionts and still preserve distinct genes for important functions like making ATP. To speed the emerging therapeutic research into the ...

Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death.

Scientists have discovered a mechanism called excitation-mitochondrial DNA transcription coupling (E-TCmito) that links neuronal activity to mitochondrial function. This mechanism plays a critical ...

In a significant advancement for Parkinson’s Disease (PD) therapy, researchers have developed a targeted nano formulation ...