For one, microglia hovering around plaques—the type that express the most TREM2—reportedly become desensitized to stimulation ...

Researchers have developed engineered human microglia that detect disease-related brain changes and release therapeutic ...

Microglia can be engineered to detect disease-specific brain changes – like amyloid plaques in Alzheimer’s disease – and ...

Microglia degrade plaques, but they are also known to contribute to the formation of plaques. This paradox was intriguing, and the researchers wondered if digestive exophagy could play a role in ...

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease ...

They constantly scan the brain for signs of trouble – like pathogens ... digesting harmful substances in a process called phagocytosis. Microglia also help regulate inflammation and support ...

A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and ...

Image Credit: Axol Bioscience Ltd To evaluate the functional performance of the axoCells Microglia, Axol conducted various assays, such as phagocytosis, chemotaxis, and cytokine release ...