Drug metabolism is the term used to describe the biotransformation of pharmaceutical substances in the body so that they can be eliminated more easily. The majority of metabolic processes that ...

Additionally, recombinant P450s (E. coli expressed recombinant enzymes) can be employed to determine the specific enzymes involved in drug metabolism (e.g., CYP1A2, 2C8, 2C9, 2C19, and CYP3A4).

Safety Assessment of Drug Metabolites January 15, 2010. By Graham A. McGibbon, PhD , Pranas Japertas, PhD and Sanjivanjit K Bhal, PhD . January 15, 2010 ...

Codexis®, Inc. has introduced the Codex™ MicroCyp Plate, a research productivity tool which can be used by pharmaceutical companies to identify and synthesize drug metabolites and novel drug lead ...

The findings were described in a pair of studies published in the journal Drug Metabolism and Disposition. One study focused on a family of enzymes known as cytochrome P450s ...