Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

Sphingolipids are named for the enigmatic ... Manzo et al, Rewiring Endothelial Sphingolipid Metabolism to Favor S1P Over ...

Disorders in endogenous lipid metabolism have been associated with ... and phospholipids, sphingolipids, cholesterol and oxysterols as representatives of membrane lipids within the CNS.