Meperidine Oral Solution prescription and dosage information for physicians and health care professionals. ... from the accumulation of the meperidine metabolite, normeperidine.

Meperidine by itself, on the other hand, produced a 25 per cent average depression of inspiratory minute ventilation from a mean of 5.10 liters (S.E. ± 0.43) to a mean of 3.85 ± 0.44 liters ...

Due to renally cleared metabolites, some opioids, such as morphine, should be used with caution among older adults. Others, such as meperidine, should never be used at all. When prescribing or ...