They can make gene delivery easy and efficient in a number of models of disease. The Vector Development Laboratory is located within the Cell and Gene Therapy Center on the 10th floor of the Alkek ...

As these vectors progress to the next level of phase I and phase II clinical studies, it is important to establish vector purification schemes that are both amenable to large-scale production and ...

This cassette is then transferred to the adenovirus vector plasmid (pAdeno X, Clontech Laboratories or pAd5F35, The Journal of Gene Medicine Volume 6, Issue 6 , Pages 631 - 641). The adenovirus vector ...

Previous efforts to circumvent the problem of the size limitation imposed by the AAV vector have focused mainly on altering the candidate genes into ‘mini-expression cassettes’ suitable for ...