随着免疫血清学检测技术的进步，抗中性粒细胞胞浆抗体（ANCA），尤其是针对髓过氧化物酶（MPO）和蛋白酶 3（PR3）的 ANCA，在 AAV 的发病机制和诊断中的重要性日益凸显。MPO-ANCA 与 MPA 密切相关，PR3-ANCA 则更多地出现在 GPA 患者中。基于此，利用 ANCA 特异性来 ...

Today, the most appropriate way to detect the presence of vasculitis-associated ANCA is by using immunofluorescence testing together with PR3-ANCA and MPO-ANCA ELISAs. The answer to problems ...

A significant percentage of patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) demonstrate coronary artery calcification (CAC) on imaging, with variations by ANCA ...

A significant percentage of patients with RA and ANCA positivity were also diagnosed with AAV, with GPA being the most common subtype.

Treatment results in remission for about 85% of patients with antineutrophil cytoplasmic antibody (ANCA)-associated small-vessel vasculitis; however, 11–57% of these suffer relapse, which can ...

Cutaneous vasculitis (CV) is a term used for ... P-ANCA positive with perinuclear pattern (anti-myeloperoxidase [MPO]). He is negative for C-ANCA antibodies (serine proteinase-3 [3-PR3]).

Vasculitis in pregnancy is probably underdiagnosed and under-reported; cases of vasculitis are rare and so disease flares may not always be recognized by a general clinician. Preconceptual ...