MMP-2 is secreted as a proenzyme that ... Researchers had previously mapped the structure of limited portions of the protein, but Karl Tryggvason and colleagues from the Karolinska Institute ...

Koivunen et al. (pp. 749 and 768) describe the use of phage panning to isolate a cyclic peptide that selectively targets MMPs most closely associated with metastatic potential, and homes to ...