2.6 Uptake of Dil-ox-LDL into macrophages The Dil-ox-LDL uptake assay ... Jansen et al. (23) have shown that exosomes from high glucose-pretreated ECs facilitate M1 macrophage infiltration and the ...

Intraluminal vesicles from multivesicular bodies release exosomes into the extracellular space. Exosomes move to M0 macrophages and modulate the polarization into M1 and M2 under different stimulation ...

smu.edu.cn, baixc15{at}smu.edu.cn Objectives To investigate the roles and regulatory mechanisms of synovial macrophages and their polarisation in the development of osteoarthritis (OA). Methods ...

Enumeration of foam cells were performed by microscopy and lipid accumulation was quantified by isopropanol wash assay. Results We observed that AcLDL uptake by M1 and M4 macrophages were lower when ...

M2 macrophages are associated with wound healing by the production of arginase-1 [2,3]. Synovial macrophages are of critical importance in the symptomatology and structural progression of OA since M1 ...