Lysosomes may also fuse with phagosomes and autophagosomes. Some phagocytosed pathogens can prevent or delay phagolysosome biogenesis; others escape their intracellular vacuole by degrading the ...

Microautophagy of endosomes delivers the membranes of both plasma membrane/endosome and lysosome/vacuole origins into the lumen of the apical vacuoles where digestive enzymes including lipases are ...

USA), describes a study performed in yeast to investigate the effects of uncoupling the mitochondria from the vacuole-heavy lysosomes. By severing the connection between the two organelles and ...

This also ensures that more vacuoles are present than the number of lysosomes which can digest them. In the study published in Microbes and Infection, the IISc team deduced that a critical protein ...

This also ensures that more vacuoles are present than the number of lysosomes which can digest them. In the study published in Microbes and Infection, the IISc team deduced that a critical protein ...

The lysosome was once thought of as the trash can of the cell, a dead-end destination where cellular debris was sent for disposal. But a growing body of research shows that this enzyme-filled ...

In the main form of autophagy, materials floating in the cell are transported to specialized organelles, such as lysosomes or vacuoles, within small capsule-like structures called autophagosomes.

The completed autophagosome then fuses with a lysosome or a vacuole [2] and the materials inside the autophagosome are degraded by enzymes inside the lysosome or vacuole. Many Atg proteins playing ...

The problem in AD dystrophic neurons, it seems, is that lysosomes are unable to keep up with the production of autophagic vacuoles. This suggestion has implications not only for AD, but for other ...

The scientists tracked waste removal in cells with imaging tools, and found that some lysosomes got bigger; they were merging with autophagic vacuoles, which were stuffed with waste that wasn't broken ...