The mechanisms underlying autophagy and its relevance both in ... intriguing questions. How does lysosome number, size and content vary in different cell types, in different tissues or in ...

There are several types of vesicle, including transport ... If a cell has absorbed something harmful, such as a pathogen, it can use its lysosomes to ingest those bacteria and destroy them with ...

Scientists have discovered how iron in lysosomes can induce ferroptosis, offering a new route to target treatment-resistant cancer cells and stop metastasis. Ferroptosis has been gathering an ...

Lastly, in autophagy, the cell cleans up its own damaged parts, such as old mitochondria, by wrapping them in a membrane bubble called an autophagosome. This bubble then merges with the lysosome ...

Osaka University and Nara Medical University researchers reveal microautophagy's role in repairing damaged lysosomes, a breakthrough with implications for aging, cellular health, and potential ...

In many neurodegenerative disorders, microglia come down with a kind of indigestion, and no longer degrade lipids and other molecules ... blocking the signaling molecule sCD22 restored lysosome ...