Using a staining method for acid phosphatase, de Duve and Novikoff confirmed its location ... we know that lysosomes contain hydrolases that are capable of digesting all kinds of macromolecules.

Lysosome-related organelles ... complex and incompletely understood. Its organelles and constituents vary between different cell types, but endolysosomal proteases are key components of this ...

Lastly, in autophagy, the cell cleans up its own damaged parts, such as old mitochondria, by wrapping them in a membrane bubble called an autophagosome. This bubble then merges with the lysosome ...