Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium ...

Lysosomes are dynamic organelles that receive membrane traffic input from the secretory, endocytic, autophagic and phagocytic pathways. They can also fuse with the plasma membrane. Live-cell ...

In a paper published in Nature Communications, researchers from Kyushu University, using cultured cells and mice, found that the lipid peroxidation of the lysosomes—the organelle responsible for ...

How are relationships or interactions between different organelles illustrated ... bound organelles Endosome transport from the Golgi or Plasma Membrane to the Lysosome Using animated or active models ...

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer—lysosomal membrane ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes.

Scientists have identified a new organelle in liver cells called the mitochondria-lysosome-related organelle (MLRO). This discovery could improve our understanding of chronic liver diseases like ...

Lysosomes are surrounded by a lipid bilayer that separates the acidic environment and the digestive enzymes of the organelle from the cytoplasm. Damage to this layer - lysosomal membrane ...

More information: Xiaowen Ma et al, Perspectives of mitochondria-lysosome-related organelle in hepatocyte dedifferentiation and implications in chronic liver disease, eGastroenterology (2024). DOI ...

(1) Degradation of mitochondria matrix, inner membrane and intermembrane oxidised or misfolded protein by mitochondrial proteases. (2) Ubiquitinated outer mitochondrial membrane proteins are ...

But we know less about the role of ions inside the individual parts inside the cell. These are the organelles—the Golgi bodies, the lysosomes, the mitochondria, etc., which each carry out special ...

In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal ...