Lysosome-related organelles (LROs ... particularly in the immune system. For example, the LROs of mast cells contain lipid mediators, histamine, heparin and tryptase and chymase proteases ...

Feng Wei at the Institute of Biophysics, Chinese Academy of Sciences, has made significant strides in understanding the BORC complex, a key player in lysosome transport and localization.

Fats and other cellular materials reach the lysosome through three main pathways: endocytosis, phagocytosis, and autophagy. In endocytosis, the cell takes in materials from outside by wrapping ...